Small molecules which reverse ESRRB Mutation - (ERR-beta; NR3B2)
Canned Analysis
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General Information
AccessionDCA00019778
TitleSmall molecules which reverse ESRRB Mutation - (ERR-beta; NR3B2)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ESRRB Mutation - (ERR-beta; NR3B2) in the Stria vascularis cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2318ee467bea600fbb716
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1047
Cell TypeStria vascularis
Gene Symbol (human)ESRRB
Gene Symbol (mouse)Esrrb
Organismmouse
Perturbation TypeMutation - (ERR-beta; NR3B2)
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM209600, GSM209601, GSM209602
Perturbed SamplesGSM209603, GSM209604, GSM209605
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8434
Gene Expression Omnibus
Estrogen-related receptor beta mutation effect on the stria vascularis
7
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