Small molecules which reverse NFE2L2 Deficiency
Canned Analysis
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General Information
AccessionDCA00019780
TitleSmall molecules which reverse NFE2L2 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NFE2L2 Deficiency in the Lung epithelial cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2317be467bea600fbb70e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1048
Cell TypeLung epithelial cell
Gene Symbol (human)NFE2L2
Gene Symbol (mouse)Nfe2l2
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM189472, GSM189473
Perturbed SamplesGSM189476, GSM189477
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7810
Gene Expression Omnibus
Nrf2-deficient type II lung epithelial cell response to antioxidant supplementation
7
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