Small molecules which mimic MUC2 "missense mutation (T2996C, Accession AJ511873) resulting i
Canned Analysis
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General Information
AccessionDCA00019787
TitleSmall molecules which mimic MUC2 "missense mutation (T2996C, Accession AJ511873) resulting i
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by MUC2 "missense mutation (T2996C, Accession AJ511873) resulting i in the Large Intestine (Distal and Proximal) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d236eee467bea600fbb976
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCesarPrada
CREEDS IDgene:1053
Cell TypeLarge Intestine (Distal and Proximal)
Gene Symbol (human)MUC2
Gene Symbol (mouse)Muc2
Organismmouse
Perturbation Type"missense mutation (T2996C, Accession AJ511873) resulting i
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM250853, GSM250854, GSM250855
Perturbed SamplesGSM250847, GSM250848, GSM250849
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9913
Gene Expression Omnibus
Intestinal gene expression in ENU mutagenesis mouse strains with missense mutations in Muc2 mucin and ER stress
14
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