Small molecules which mimic GATA1 KO
Canned Analysis
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General Information
AccessionDCA00019799
TitleSmall molecules which mimic GATA1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by GATA1 KO in the CD4+ CD25hi Tregs cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23c75e467bea600fbbbe6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1062
Cell TypeCD4+ CD25hi Tregs
Gene Symbol (human)GATA1
Gene Symbol (mouse)Gata1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM990134, GSM990135
Perturbed SamplesGSM990132, GSM990133
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40273
Gene Expression Omnibus
Gene expression profiling in Treg cells deficient or mutant in candidate FoxP3 cofactors
21
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