Small molecules which reverse TWIST1 OE
Canned Analysis
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General Information
AccessionDCA00019812
TitleSmall molecules which reverse TWIST1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by TWIST1 OE in the prostate cancer cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f35ae467bea600fb9c30
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsolomoniyi
CREEDS IDgene:1077
Cell Typeprostate cancer
Gene Symbol (human)TWIST1
Gene Symbol (mouse)Twist1
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1211847, GSM1211852, GSM1211857
Perturbed SamplesGSM1211851, GSM1211856, GSM1211861
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE50002
Gene Expression Omnibus
Prostate cancer cell line response to overexpression of Twist1 and Twist1 mutants
42
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