Small molecules which reverse TFAM KD
Canned Analysis
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General Information
AccessionDCA00019820
TitleSmall molecules which reverse TFAM KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by TFAM KD in the murine embryonic fibroblasts (MEFs) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f33fe467bea600fb9c24
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorchrisliu
CREEDS IDgene:1074
Cell Typemurine embryonic fibroblasts (MEFs)
Gene Symbol (human)TFAM
Gene Symbol (mouse)Tfam
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1556844, GSM1556845
Perturbed SamplesGSM1556846, GSM1556847
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE63767
Gene Expression Omnibus
Expression analysis of wild-type and Tfam heterozygous knockout (Tfam+/-) murine embryonic fibroblasts (MEFs).
7
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