Small molecules which mimic GATA1 KD
Canned Analysis
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General Information
AccessionDCA00019825
TitleSmall molecules which mimic GATA1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by GATA1 KD in the megakaryocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22750e467bea600fbb290
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:108
Cell Typemegakaryocytes
Gene Symbol (human)GATA1
Gene Symbol (mouse)Gata1
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM48233, GSM48234, GSM48235
Perturbed SamplesGSM48230, GSM48231, GSM48232
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2527
Gene Expression Omnibus
GATA-1 knockdown effect on megakaryocytes
12
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