Small molecules which reverse IFNG KO
Canned Analysis
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General Information
AccessionDCA00019848
TitleSmall molecules which reverse IFNG KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IFNG KO in the CD71+ bone marrow cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f1d8e467bea600fb9b88
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1108
Cell TypeCD71+ bone marrow cells
Gene Symbol (human)IFNG
Gene Symbol (mouse)Ifng
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM562023, GSM562024, GSM562025
Perturbed SamplesGSM562029, GSM562030, GSM562031
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE22656
Gene Expression Omnibus
Expression data from CD71+ cells from the bone marrow of WT, CD70TG, IFNg-/- and CD70TG*IFNg-/- mice.
14
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