Small molecules which mimic TNF siTNF
Canned Analysis
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General Information
AccessionDCA00019851
TitleSmall molecules which mimic TNF siTNF
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by TNF siTNF in the Colon cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d233d5e467bea600fbb816
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1111
Cell TypeColon
Gene Symbol (human)TNF
Gene Symbol (mouse)Tnf
Organismmouse
Perturbation TypesiTNF
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM790907, GSM790908, GSM790909, GSM790910, GSM790911, GSM790912, GSM790913, GSM790914, GSM790915
Perturbed SamplesGSM790923, GSM790924, GSM790925, GSM790926, GSM790927, GSM790928
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE31906
Gene Expression Omnibus
DSS-induced colitis model response to enhanced siRNA targeting of Tumor necrosis factor
28
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