Small molecules which reverse TNF siTNF-OMe
Canned Analysis
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General Information
AccessionDCA00019854
TitleSmall molecules which reverse TNF siTNF-OMe
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by TNF siTNF-OMe in the Colon cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d233cee467bea600fbb814
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1113
Cell TypeColon
Gene Symbol (human)TNF
Gene Symbol (mouse)Tnf
Organismmouse
Perturbation TypesiTNF-OMe
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM790907, GSM790908, GSM790909, GSM790910, GSM790911, GSM790912, GSM790913, GSM790914, GSM790915
Perturbed SamplesGSM790929, GSM790930, GSM790931, GSM790932, GSM790933, GSM790934
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE31906
Gene Expression Omnibus
DSS-induced colitis model response to enhanced siRNA targeting of Tumor necrosis factor
28
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