Small molecules which reverse CXCL8 human IL8 transgenic
Canned Analysis
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General Information
AccessionDCA00019862
TitleSmall molecules which reverse CXCL8 human IL8 transgenic
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CXCL8 human IL8 transgenic in the Colon cancer tumor, CBA/C57BL/6 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23b92e467bea600fbbb82
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1118
Cell TypeColon cancer tumor, CBA/C57BL/6
Gene Symbol (human)CXCL8
Organismmouse
Perturbation Typehuman IL8 transgenic
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM959587, GSM959588, GSM959589
Perturbed SamplesGSM959590, GSM959591, GSM959592
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE39273
Gene Expression Omnibus
Effect of transgenic human IL8 on gene expression in mouse colon cancer tumors
7
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