Small molecules which reverse NOD2 KO
Canned Analysis
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General Information
AccessionDCA00019868
TitleSmall molecules which reverse NOD2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NOD2 KO in the bone-marrow derived macrophages cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d235f4e467bea600fbb908
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1122
Cell Typebone-marrow derived macrophages
Gene Symbol (human)NOD2
Gene Symbol (mouse)Nod2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM913135, GSM913136, GSM913137
Perturbed SamplesGSM913141, GSM913142, GSM913143
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE37179
Gene Expression Omnibus
Expression data from infected with Neisseria gonorrhoeae (GC) and uninfected bone marrow derived macrophages from wild type (C67BL/6) and Nod2 knock o...
7
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