Small molecules which reverse AGER KO
Canned Analysis
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General Information
AccessionDCA00019884
TitleSmall molecules which reverse AGER KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by AGER KO in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d235ebe467bea600fbb904
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1125
Cell Typeliver
Gene Symbol (human)AGER
Gene Symbol (mouse)Ager
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM565136, GSM565137, GSM565138, GSM565139, GSM565140
Perturbed SamplesGSM565141, GSM565142, GSM565143, GSM565144, GSM565145, GSM565146
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE22873
Gene Expression Omnibus
Ager (Rage) and Myd88 deletion in resected mouse livers
14
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