Small molecules which reverse MYD88 KO
Canned Analysis
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General Information
AccessionDCA00019890
TitleSmall molecules which reverse MYD88 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MYD88 KO in the colon, adenocarcinoma cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23622e467bea600fbb91c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1128
Cell Typecolon, adenocarcinoma
Gene Symbol (human)MYD88
Gene Symbol (mouse)Myd88
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM494372, GSM494373, GSM494374, GSM494375, GSM494376, GSM494377
Perturbed SamplesGSM494378, GSM494379, GSM494380, GSM494381, GSM494382, GSM494383
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE19793
Gene Expression Omnibus
MyD88-mediated signaling prevents development of adenocarcinomas of the colon via interleukin-18
7
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