Small molecules which reverse E2F1 OE
Canned Analysis
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General Information
AccessionDCA00019892
TitleSmall molecules which reverse E2F1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by E2F1 OE in the SK-MEL-2 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2362ce467bea600fbb920
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormauroccm
CREEDS IDgene:1129
Cell TypeSK-MEL-2
Gene Symbol (human)E2F1
Gene Symbol (mouse)E2f1
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM52504, GSM52508
Perturbed SamplesGSM52518, GSM52519
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2715
Gene Expression Omnibus
Melanoma cell line response to E2F-1 overexpression and doxorubicin treatment
7
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