Small molecules which reverse IFNAR2 KO
Canned Analysis
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General Information
AccessionDCA00019910
TitleSmall molecules which reverse IFNAR2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IFNAR2 KO in the bone-marrow derived macrophages cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2309ee467bea600fbb6ae
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1139
Cell Typebone-marrow derived macrophages
Gene Symbol (human)IFNAR2
Gene Symbol (mouse)Ifnar2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1111106, GSM1111107
Perturbed SamplesGSM1111108, GSM1111109
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE45632
Gene Expression Omnibus
Differential induction of TLR3-dependent innate immune signaling by closely related parasite species_I
7
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