Small molecules which reverse SRF KO
Canned Analysis
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General Information
AccessionDCA00019938
TitleSmall molecules which reverse SRF KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SRF KO in the Embryonic Stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fda1e467bea600fba06e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1158
Cell TypeEmbryonic Stem cells
Gene Symbol (human)SRF
Gene Symbol (mouse)Srf
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM34819, GSM34820, GSM34826, GSM34827, GSM34834, GSM34835
Perturbed SamplesGSM34823, GSM34824, GSM34830, GSM34831, GSM34838, GSM34839
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1948
Gene Expression Omnibus
Serum response factor SRF overexpression in embryonic stem cells
70
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