Small molecules which reverse SRF homozygous Srf mutant 81 (vector control treatment)
Canned Analysis
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General Information
AccessionDCA00019942
TitleSmall molecules which reverse SRF homozygous Srf mutant 81 (vector control treatment)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SRF homozygous Srf mutant 81 (vector control treatment) in the embryonic stem (ES) cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d203e2e467bea600fba332
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsolomoniyi
CREEDS IDgene:1393
Cell Typeembryonic stem (ES) cell
Gene Symbol (human)SRF
Gene Symbol (mouse)Srf
Organismmouse
Perturbation Typehomozygous Srf mutant 81 (vector control treatment)
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM34819, GSM34820
Perturbed SamplesGSM34823, GSM34824
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1948
Gene Expression Omnibus
Serum response factor SRF overexpression in embryonic stem cells
70
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