Small molecules which mimic GATA6 KO
Canned Analysis
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General Information
AccessionDCA00019963
TitleSmall molecules which mimic GATA6 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by GATA6 KO in the Lung cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2219ce467bea600fbb010
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorshvetank
CREEDS IDgene:1165
Cell TypeLung
Gene Symbol (human)GATA6
Gene Symbol (mouse)Gata6
Organismmouse
Perturbation TypeKO
None{u'vals': [0.147693671045, -0.101106534388, 0.0985150979138, 0.0860236275156, 0.0835196896709, -0.0788378956166, 0.078326266347, -0.0760354815806, -0.0756679239716, 0.0711662549343, 0.0692143608925, -0.0665146819096, -0.0657079862933, 0.065623251333, -0.0
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM281658, GSM281659, GSM281660
Perturbed SamplesGSM281661, GSM281662, GSM281663
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11165
Gene Expression Omnibus
Genes regulated by GATA6 in the lung
7
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