Small molecules which mimic E2F4 KO
Canned Analysis
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General Information
AccessionDCA00019965
TitleSmall molecules which mimic E2F4 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by E2F4 KO in the MEF cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2218ae467bea600fbb008
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorshvetank
CREEDS IDgene:1167
Cell TypeMEF cells
Gene Symbol (human)E2F4
Gene Symbol (mouse)E2f4
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM278989, GSM278990, GSM278991, GSM278992, GSM278993, GSM278994, GSM278995, GSM278996, GSM278997, GSM278998
Perturbed SamplesGSM278999, GSM279000, GSM279001, GSM279002, GSM279003, GSM279004, GSM279005, GSM279006, GSM279007, GSM279008
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11039
Gene Expression Omnibus
Expression Data from wild type and E2F4 null MEFs
7
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