Small molecules which reverse NXNL1 Deficiency
Canned Analysis
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General Information
AccessionDCA00019972
TitleSmall molecules which reverse NXNL1 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NXNL1 Deficiency in the Retina - Heterozygous null cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21b41e467bea600fbad76
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1174
Cell TypeRetina - Heterozygous null
Gene Symbol (human)NXNL1
Gene Symbol (mouse)Nxnl1
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM349023, GSM349026, GSM349029
Perturbed SamplesGSM349024, GSM349027
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE13869
Gene Expression Omnibus
Rod-derived cone viability factor deficiency effect on the retina
14
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