Small molecules which reverse XIAP Depletion - Early passage
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00019976
TitleSmall molecules which reverse XIAP Depletion - Early passage
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by XIAP Depletion - Early passage in the HCT116 colon cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21b24e467bea600fbad6a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1170
Cell TypeHCT116 colon cancer cells
Gene Symbol (human)XIAP
Gene Symbol (mouse)Xiap
Organismhuman
Perturbation TypeDepletion - Early passage
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM294818, GSM294819
Perturbed SamplesGSM294806, GSM294807, GSM294808, GSM294809
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11618
Gene Expression Omnibus
X-linked inhibitor of apoptosis XIAP depletion effect on a colorectal cancer cell line
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.