Small molecules which mimic XIAP DEPLETION -Late passage
Canned Analysis
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General Information
AccessionDCA00019977
TitleSmall molecules which mimic XIAP DEPLETION -Late passage
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by XIAP DEPLETION -Late passage in the HCT116 colon cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21b18e467bea600fbad64
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1171
Cell TypeHCT116 colon cancer cells
Gene Symbol (human)XIAP
Gene Symbol (mouse)Xiap
Organismhuman
Perturbation TypeDEPLETION -Late passage
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM294818, GSM294819
Perturbed SamplesGSM294810, GSM294811, GSM294812, GSM294813
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11618
Gene Expression Omnibus
X-linked inhibitor of apoptosis XIAP depletion effect on a colorectal cancer cell line
14
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