Small molecules which reverse HNF4A DEPLETION
Canned Analysis
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General Information
AccessionDCA00019992
TitleSmall molecules which reverse HNF4A DEPLETION
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HNF4A DEPLETION in the HepG2 hepatocellular carcinoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22c3ee467bea600fbb4c2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:118
Cell TypeHepG2 hepatocellular carcinoma cells
Gene Symbol (human)HNF4A
Gene Symbol (mouse)Hnf4a
Organismhuman
Perturbation TypeDEPLETION
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM720617, GSM720619
Perturbed SamplesGSM720616, GSM720618
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE29084
Gene Expression Omnibus
Hepatocyte nuclear factor 4 alpha depletion effect on hepatocellular carcinoma cell line
12
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