Small molecules which reverse SOCS3 Constitutive expression
Canned Analysis
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General Information
AccessionDCA00020006
TitleSmall molecules which reverse SOCS3 Constitutive expression
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SOCS3 Constitutive expression in the Skeletal muscles cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22119e467bea600fbafd6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1189
Cell TypeSkeletal muscles
Gene Symbol (human)SOCS3
Gene Symbol (mouse)Socs3
Organismmouse
Perturbation TypeConstitutive expression
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM426843, GSM426844, GSM426845
Perturbed SamplesGSM426840, GSM426841, GSM426842
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE17063
Gene Expression Omnibus
Suppressor of cytokine signaling 3 expression effect on skeletal muscles
7
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