Small molecules which mimic ALDH5A1 KO
Canned Analysis
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General Information
AccessionDCA00020041
TitleSmall molecules which mimic ALDH5A1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ALDH5A1 KO in the Cerebellum cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23afce467bea600fbbb3c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1208
Cell TypeCerebellum
Gene Symbol (human)ALDH5A1
Gene Symbol (mouse)Aldh5a1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM53371, GSM53374, GSM53377
Perturbed SamplesGSM53362, GSM53365, GSM53368
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE2866
Gene Expression Omnibus
Succinate semialdehyde dehydrogenase deficiency effect on the brain
43
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