Small molecules which mimic TGFB1I1 KD
Canned Analysis
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General Information
AccessionDCA00020053
TitleSmall molecules which mimic TGFB1I1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by TGFB1I1 KD in the U2OS, osteosarcoma cells treated with: dexamethasone (Dex) for 4h cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f2a3e467bea600fb9be2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorchrisliu
CREEDS IDgene:1212
Cell TypeU2OS, osteosarcoma cells treated with: dexamethasone (Dex) for 4h
Gene Symbol (human)TGFB1I1
Gene Symbol (mouse)Tgfb1i1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1130357, GSM1130362, GSM1130368, GSM1130370
Perturbed SamplesGSM1130351, GSM1130373, GSM1130382, GSM1130391
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE46448
Gene Expression Omnibus
Hydrogen peroxide-inducible clone-5 deficiency effect on dexamethasone-treated osteosarcoma cells: time course
28
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