Small molecules which reverse NF1 perturbation
Canned Analysis
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General Information
AccessionDCA00020062
TitleSmall molecules which reverse NF1 perturbation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NF1 perturbation in the hippoccapal tissue postnatal day 15 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f28be467bea600fb9bd8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:1219
Cell Typehippoccapal tissue postnatal day 15
Gene Symbol (human)NF1
Gene Symbol (mouse)Nf1
Organismmouse
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM25122, GSM25133, GSM25134, GSM25135
Perturbed SamplesGSM25127, GSM25137, GSM25140, GSM25141
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1482
Gene Expression Omnibus
Neurofibromatosis and neurodevelopment
60
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