Small molecules which reverse CTCF DEPLETION
Canned Analysis
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General Information
AccessionDCA00020116
TitleSmall molecules which reverse CTCF DEPLETION
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CTCF DEPLETION in the germinal vesicle (GV) oocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d230fae467bea600fbb6d6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:124
Cell Typegerminal vesicle (GV) oocytes
Gene Symbol (human)CTCF
Gene Symbol (mouse)Ctcf
Organismmouse
Perturbation TypeDEPLETION
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM296254, GSM296255, GSM296256, GSM296257, GSM296259
Perturbed SamplesGSM296250, GSM296251, GSM296252, GSM296253, GSM296261
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11664
Gene Expression Omnibus
CTCF depletion effect in oocytes
7
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