Small molecules which mimic RAG1 KO
Canned Analysis
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General Information
AccessionDCA00020117
TitleSmall molecules which mimic RAG1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by RAG1 KO in the whole lung cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20421e467bea600fba34c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1240
Cell Typewhole lung
Gene Symbol (human)RAG1
Gene Symbol (mouse)Rag1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM158136, GSM158137, GSM158144, GSM158145
Perturbed SamplesGSM158132, GSM158133, GSM158140, GSM158141
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE6858
Gene Expression Omnibus
Asthma model: lungs
7
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