Small molecules which reverse RFWD2 KD
Canned Analysis
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General Information
AccessionDCA00020120
TitleSmall molecules which reverse RFWD2 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RFWD2 KD in the LNCap cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20408e467bea600fba342
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorzero323
CREEDS IDgene:1243
Cell TypeLNCap
Gene Symbol (human)RFWD2
Gene Symbol (mouse)Rfwd2
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM689415, GSM689426, GSM689433, GSM689434
Perturbed SamplesGSM689416, GSM689419, GSM689420, GSM689423, GSM689429, GSM689436
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE27914
Gene Expression Omnibus
LNCap prostate cancer cell line response to loss of COnstitutive Photomorphogenic-1, ETV1 and c-JUN
7
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