Small molecules which mimic NCOA1 KD
Canned Analysis
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General Information
AccessionDCA00020123
TitleSmall molecules which mimic NCOA1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by NCOA1 KD in the LY2 breast cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f627e467bea600fb9d66
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorudicuty
CREEDS IDgene:888
Cell TypeLY2 breast cancer cells
Gene Symbol (human)NCOA1
Gene Symbol (mouse)Ncoa1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM709770, GSM709773, GSM709774, GSM709776
Perturbed SamplesGSM709765, GSM709771, GSM709772, GSM709775
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE28645
Gene Expression Omnibus
Tamoxifen effect on SRC-1-deficient endocrine-resistant breast cancer cell line LY2
28
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