Small molecules which reverse E2F1 KD
Canned Analysis
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General Information
AccessionDCA00020128
TitleSmall molecules which reverse E2F1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by E2F1 KD in the Mammary tumors cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23d1de467bea600fbbc30
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:473
Cell TypeMammary tumors
Gene Symbol (human)E2F1
Gene Symbol (mouse)E2f1
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM606143, GSM606144, GSM606145, GSM606146, GSM606147, GSM606148, GSM606149, GSM606150, GSM606151, GSM606152, GSM606153, GSM606154, GSM606155, GSM606156, GSM606157, GSM606158, GSM606159, GSM606160, GSM606161, GSM606162
Perturbed SamplesGSM606163, GSM606164, GSM606165, GSM606166, GSM606167, GSM606168, GSM606169, GSM606170, GSM606171, GSM606172, GSM606173, GSM606174, GSM606175, GSM606176, GSM606177, GSM606178, GSM606179, GSM606180, GSM606181, GSM606182
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE24594
Gene Expression Omnibus
E2F transcription factor knockdown effect on Myc-induced mammary tumors
31
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