Small molecules which mimic E2F2 KD
Canned Analysis
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General Information
AccessionDCA00020129
TitleSmall molecules which mimic E2F2 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by E2F2 KD in the Mammary tumors (Myc-induced) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23cdae467bea600fbbc12
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:474
Cell TypeMammary tumors (Myc-induced)
Gene Symbol (human)E2F2
Gene Symbol (mouse)E2f2
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM606143, GSM606144, GSM606145, GSM606146, GSM606147, GSM606148, GSM606149, GSM606150, GSM606151, GSM606152, GSM606153, GSM606154, GSM606155, GSM606156, GSM606157, GSM606158, GSM606159, GSM606160, GSM606161, GSM606162
Perturbed SamplesGSM606183, GSM606184, GSM606185, GSM606186, GSM606187, GSM606188, GSM606189, GSM606190, GSM606191, GSM606192, GSM606193, GSM606194, GSM606195, GSM606196, GSM606197, GSM606198, GSM606199, GSM606200, GSM606201, GSM606202
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE24594
Gene Expression Omnibus
E2F transcription factor knockdown effect on Myc-induced mammary tumors
31
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