Small molecules which reverse E2F3 KD
Canned Analysis
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General Information
AccessionDCA00020132
TitleSmall molecules which reverse E2F3 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by E2F3 KD in the Mammary tumors (Myc-induced) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23ce6e467bea600fbbc18
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:475
Cell TypeMammary tumors (Myc-induced)
Gene Symbol (human)E2F3
Gene Symbol (mouse)E2f3
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM606143, GSM606144, GSM606145, GSM606146, GSM606147, GSM606148, GSM606149, GSM606150, GSM606151, GSM606152, GSM606153, GSM606154, GSM606155, GSM606156, GSM606157, GSM606158, GSM606159, GSM606160, GSM606161, GSM606162
Perturbed SamplesGSM606203, GSM606204, GSM606205, GSM606206, GSM606207, GSM606208, GSM606209, GSM606210, GSM606211, GSM606212, GSM606213, GSM606214, GSM606215, GSM606216, GSM606217, GSM606218, GSM606219, GSM606220, GSM606221, GSM606222
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE24594
Gene Expression Omnibus
E2F transcription factor knockdown effect on Myc-induced mammary tumors
31
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