Small molecules which mimic NET1 knock-down (63 shRNA, with lysophosphatidic acid agent treatment
Canned Analysis
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General Information
AccessionDCA00020133
TitleSmall molecules which mimic NET1 knock-down (63 shRNA, with lysophosphatidic acid agent treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by NET1 knock-down (63 shRNA, with lysophosphatidic acid agent treatment in the AGS gastric cancer (GC) cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2042be467bea600fba350
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsolomoniyi
CREEDS IDgene:1247
Cell TypeAGS gastric cancer (GC) cell
Gene Symbol (human)NET1
Gene Symbol (mouse)Net1
Organismhuman
Perturbation Typeknock-down (63 shRNA, with lysophosphatidic acid agent treatment
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM646069, GSM646070
Perturbed SamplesGSM646065, GSM646066
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE26309
Gene Expression Omnibus
Lysophosphatidic acid effect on RhoA GEF Exchange Factor NET1-deficient, AGS gastric adenocarcinoma cells
49
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