Small molecules which reverse SIN3A KD
Canned Analysis
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General Information
AccessionDCA00020146
TitleSmall molecules which reverse SIN3A KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SIN3A KD in the MCF7 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20ccbe467bea600fba71e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorudicuty
CREEDS IDgene:826
Cell TypeMCF7
Gene Symbol (human)SIN3A
Gene Symbol (mouse)Sin3a
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM873553, GSM873556, GSM873560
Perturbed SamplesGSM873555, GSM873558, GSM873562
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE35696
Gene Expression Omnibus
Leukemia inhibitory factor effect on Sin3a-silenced MCF7 breast cancer cell line
21
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