Small molecules which reverse MTDH DEPLETION
Canned Analysis
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General Information
AccessionDCA00020148
TitleSmall molecules which reverse MTDH DEPLETION
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MTDH DEPLETION in the LM2 breast cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23103e467bea600fbb6da
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:125
Cell TypeLM2 breast cancer cells
Gene Symbol (human)MTDH
Gene Symbol (mouse)Mtdh
Organismhuman
Perturbation TypeDEPLETION
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM232034, GSM232035, GSM232036
Perturbed SamplesGSM232037, GSM232038, GSM232039
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9187
Gene Expression Omnibus
Lung metastatic breast cancer cell line response to metadherin depletion
14
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