Small molecules which mimic COMMD3-BMI1 KD
Canned Analysis
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General Information
AccessionDCA00020229
TitleSmall molecules which mimic COMMD3-BMI1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by COMMD3-BMI1 KD in the DAOY medulloblastoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23114e467bea600fbb6e0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:129
Cell TypeDAOY medulloblastoma cells
Gene Symbol (human)COMMD3-BMI1
Gene Symbol (mouse)Bmi1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM182018, GSM182019, GSM182020
Perturbed SamplesGSM182006, GSM182007, GSM182008
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7578
Gene Expression Omnibus
Transcriptional regulators Bmi-1 and Mel-18 depletion effect on medulloblastoma cell line
21
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