Small molecules which mimic ABCA1 Heterozygotic knockout (Abca1+/-)
Canned Analysis
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General Information
AccessionDCA00020243
TitleSmall molecules which mimic ABCA1 Heterozygotic knockout (Abca1+/-)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ABCA1 Heterozygotic knockout (Abca1+/-) in the Liver tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2346de467bea600fbb85a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:1293
Cell TypeLiver tissue
Gene Symbol (human)ABCA1
Gene Symbol (mouse)Abca1
Organismmouse
Perturbation TypeHeterozygotic knockout (Abca1+/-)
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM9281, GSM9282
Perturbed SamplesGSM9283, GSM9284
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE614
Gene Expression Omnibus
Embryonic stem cell cholesterol metabolism mutants
35
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