Small molecules which reverse UTRN OE
Canned Analysis
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General Information
AccessionDCA00020254
TitleSmall molecules which reverse UTRN OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by UTRN OE in the mdx mouse muscle cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2348ae467bea600fbb868
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcms
CREEDS IDgene:1296
Cell Typemdx mouse muscle
Gene Symbol (human)UTRN
Gene Symbol (mouse)Utrn
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM172904, GSM172905, GSM172906, GSM172907, GSM172908, GSM172909
Perturbed SamplesGSM172899, GSM172900, GSM172901, GSM172902, GSM172903
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7187
Gene Expression Omnibus
Utrophin overexpression effect on dystrophin-deficient mdx skeletal muscles
14
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