Small molecules which reverse DMD mutation leading to lack of expression (mdx mutant)
Canned Analysis
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General Information
AccessionDCA00020256
TitleSmall molecules which reverse DMD mutation leading to lack of expression (mdx mutant)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DMD mutation leading to lack of expression (mdx mutant) in the muscle cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d213cce467bea600fbaa32
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curator
CREEDS ID
Cell Type
Gene Symbol (human)
Gene Symbol (mouse)
Organism
Perturbation Type
L1000CDS2 parameters
Direction
Characteristic Direction parameters
Control Samples
Perturbed Samples
Tools used in the analysis

Dataset Accession

L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis

Keyword
Tool Name

GSE7187
Utrophin overexpression effect on dystrophin-deficient mdx skeletal muscles
14
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