Small molecules which mimic INSR KO
Canned Analysis
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General Information
AccessionDCA00020257
TitleSmall molecules which mimic INSR KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by INSR KO in the Liver tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d213d2e467bea600fbaa34
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:1299
Cell TypeLiver tissue
Gene Symbol (human)INSR
Gene Symbol (mouse)Insr
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1602122, GSM1602123, GSM1602124
Perturbed SamplesGSM1602125, GSM1602126, GSM1602127
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE65624
Gene Expression Omnibus
Hepatic Gene Expression in LIRKO Mice
7
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