Small molecules which reverse KMT2D KD
Canned Analysis
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General Information
AccessionDCA00020260
TitleSmall molecules which reverse KMT2D KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by KMT2D KD in the keratinocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23574e467bea600fbb8d0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1301
Cell Typekeratinocytes
Gene Symbol (human)KMT2D
Gene Symbol (mouse)Kmt2d
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM921888, GSM921889
Perturbed SamplesGSM921890, GSM921891
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE37570
Gene Expression Omnibus
MLL2-depleted epidermal keratinocyte response to the induction of differentiation in vitro
7
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