Small molecules which reverse KDM6A KD
Canned Analysis
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General Information
AccessionDCA00020264
TitleSmall molecules which reverse KDM6A KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by KDM6A KD in the male embryonic stem cells WD44 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2356be467bea600fbb8cc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1303
Cell Typemale embryonic stem cells WD44
Gene Symbol (human)KDM6A
Gene Symbol (mouse)Kdm6a
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1096080, GSM1096082
Perturbed SamplesGSM1096081, GSM1096083
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE45034
Gene Expression Omnibus
Expression data from mouse ES cells after control RNAi (scramble siRNAs) or RNAi specific for Kdm6a treatment.
14
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