Small molecules which mimic MYC KD
Canned Analysis
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General Information
AccessionDCA00020267
TitleSmall molecules which mimic MYC KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by MYC KD in the Du145-PCAT1 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2354de467bea600fbb8be
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1308
Cell TypeDu145-PCAT1
Gene Symbol (human)MYC
Gene Symbol (mouse)Myc
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1325448, GSM1325450
Perturbed SamplesGSM1325442, GSM1325443
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE54872
Gene Expression Omnibus
The long noncoding RNA PCAT-1 promotes prostate cancer cell proliferation through post-transcriptional stabilization of the cMyc oncogene
28
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