Small molecules which reverse MYC KD
Canned Analysis
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General Information
AccessionDCA00020270
TitleSmall molecules which reverse MYC KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MYC KD in the RWPE-PCAT1 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23011e467bea600fbb672
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1311
Cell TypeRWPE-PCAT1
Gene Symbol (human)MYC
Gene Symbol (mouse)Myc
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1325449, GSM1325451
Perturbed SamplesGSM1325444, GSM1325446
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE54872
Gene Expression Omnibus
The long noncoding RNA PCAT-1 promotes prostate cancer cell proliferation through post-transcriptional stabilization of the cMyc oncogene
28
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