Small molecules which reverse CLPP KO
Canned Analysis
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General Information
AccessionDCA00020280
TitleSmall molecules which reverse CLPP KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CLPP KO in the brain cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23634e467bea600fbb924
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorantons
CREEDS IDgene:135
Cell Typebrain
Gene Symbol (human)CLPP
Gene Symbol (mouse)Clpp
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM988378, GSM988379, GSM988380
Perturbed SamplesGSM988375, GSM988376, GSM988377
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40207
Gene Expression Omnibus
Mitochondrial protease Clpp knockout effect on various tissues
62
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