Small molecules which mimic CLPP KO
Canned Analysis
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General Information
AccessionDCA00020281
TitleSmall molecules which mimic CLPP KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by CLPP KO in the brain, testis, liver, heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22615e467bea600fbb204
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
CREEDS IDgene:1576
Cell Typebrain, testis, liver, heart
Gene Symbol (human)CLPP
Gene Symbol (mouse)Clpp
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM988360, GSM988361, GSM988362, GSM988366, GSM988367, GSM988368, GSM988378, GSM988379, GSM988380, GSM988384, GSM988385, GSM988386
Perturbed SamplesGSM988357, GSM988358, GSM988359, GSM988363, GSM988364, GSM988365, GSM988375, GSM988376, GSM988377, GSM988381, GSM988382, GSM988383
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE40207
Gene Expression Omnibus
Mitochondrial protease Clpp knockout effect on various tissues
62
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