Small molecules which reverse PTEN KO
Canned Analysis
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General Information
AccessionDCA00020298
TitleSmall molecules which reverse PTEN KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PTEN KO in the KrasG12D pancreatic ductal epithelial cells deficient in PTEN cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23008e467bea600fbb66e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorVICENTE
CREEDS IDgene:1316
Cell TypeKrasG12D pancreatic ductal epithelial cells deficient in PTEN
Gene Symbol (human)PTEN
Gene Symbol (mouse)Pten
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM634506, GSM634507, GSM634508
Perturbed SamplesGSM634501, GSM634502, GSM634503, GSM634504, GSM634505
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE25828
Gene Expression Omnibus
KrasG12D pancreatic ductal epithelial cells deficient in PTEN
7
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